Background: Healthy lifestyle including sufficient physical activity may mitigate or prevent adverse long-term effects of\nchildhood cancer. We described daily physical activities and sports in childhood cancer survivors and controls, and assessed\ndeterminants of both activity patterns.\nMethodology/Principal Findings: The Swiss Childhood Cancer Survivor Study is a questionnaire survey including all\nchildren diagnosed with cancer 1976ââ?¬â??2003 at age 0ââ?¬â??15 years, registered in the Swiss Childhood Cancer Registry, who\nsurvived $5years and reached adulthood ($20years). Controls came from the population-based Swiss Health Survey. We\ncompared the two populations and determined risk factors for both outcomes in separate multivariable logistic regression\nmodels. The sample included 1058 survivors and 5593 controls (response rates 78% and 66%). Sufficient daily physical\nactivities were reported by 52% (n = 521) of survivors and 37% (n = 2069) of controls (p,0.001). In contrast, 62% (n = 640) of\nsurvivors and 65% (n = 3635) of controls reported engaging in sports (p = 0.067). Risk factors for insufficient daily activities in\nboth populations were: older age (OR for $35years: 1.5, 95CI 1.2ââ?¬â??2.0), female gender (OR 1.6, 95CI 1.3ââ?¬â??1.9), French/Italian\nSpeaking (OR 1.4, 95CI 1.1ââ?¬â??1.7), and higher education (OR for university education: 2.0, 95CI 1.5ââ?¬â??2.6). Risk factors for no\nsports were: being a survivor (OR 1.3, 95CI 1.1ââ?¬â??1.6), older age (OR for $35years: 1.4, 95CI 1.1ââ?¬â??1.8), migration background (OR\n1.5, 95CI 1.3ââ?¬â??1.8), French/Italian speaking (OR 1.4, 95CI 1.2ââ?¬â??1.7), lower education (OR for compulsory schooling only: 1.6,\n95CI 1.2ââ?¬â??2.2), being married (OR 1.7, 95CI 1.5ââ?¬â??2.0), having children (OR 1.3, 95CI 1.4ââ?¬â??1.9), obesity (OR 2.4, 95CI 1.7ââ?¬â??3.3), and\nsmoking (OR 1.7, 95CI 1.5ââ?¬â??2.1). Type of diagnosis was only associated with sports.\nConclusions/Significance: Physical activity levels in survivors were lower than recommended, but comparable to controls\nand mainly determined by socio-demographic and cultural factors. Strategies to improve physical activity levels could be\nsimilar as for the general population.
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